diff --git a/bundles/org.openhab.binding.comfoair/README.md b/bundles/org.openhab.binding.comfoair/README.md
index 9814efc6e..f5b96fe6c 100644
--- a/bundles/org.openhab.binding.comfoair/README.md
+++ b/bundles/org.openhab.binding.comfoair/README.md
@@ -4,6 +4,8 @@ This binding allows to monitor and control Zehnder ComfoAir serial controlled ve
 Though the binding is developed based on the protocol description for Zehnder ComfoAir devices it should also work for mostly identical systems from different manufacturers, like StorkAir WHR930, Wernig G90-380 and Paul Santos 370 DC.
 It was also successfully tested on a Wernig G90-160.
 
+**NOTE:** This binding does not work with the ComfoAir Q-series (e.g. Q350 or Q450). These ventilation units use a CAN bus for communication and a different protocol.
+
 ### Limitations
 
 * Either the ComfoAir binding or the CCEase Comfocontrol can be active, but not together.